Location : Home > Products > Inhibitors of Meditech > Receptor Tyrosine Kinases (RTK) > Bcr-Abl
Name:Ponatinib (AP24534)
| Chemical structure | Code NO. |
MT0009 |
 |
Name |
Ponatinib (AP24534) |
Synonym |
Ponatinib, AP24534 | |
CAS NO. |
943319-70-8 (Ponatinib, free base), 1114544-31-8 (Ponatinib monohydrochloride), 1232836-25-7 (Ponatinib tris-hydrochloride) | |
Chemical Formula |
C29H27F3N6O | |
MW |
532.559449 | |
Purity |
> 98% | |
Solubility(R.T.: 25℃) |
DMSO ≥107mg/mL, Water <1mg/mL , Ethanol ≥107mg/mL | |
Stability |
- 20℃, 2 years |
Availability and price
Ponatinib (AP24534) is in stock. Bulk available at low price, welcom to inquire quotation.
For quotation or order, please complete the Order On-line below. We offer big discount for bulk quantities. If you have any other questions or needs, please send email to [email protected]. We’ll reply you asap.
| Order the Product *is required. |
Batch and quality control
Description
Ponatinib (AP24534) is a novel multitargeted kinase inhibitor that potently inhibits native and mutant BCR-ABL at clinically achievable drug levels. Ponatinib also has in vitro inhibitory activity against a discrete set of kinases implicated in the pathogenesis of other hematologic malignancies, including FLT3, KIT, fibroblast growth factor receptor 1 (FGFR1), and platelet derived growth factor receptor α (PDGFRα).[1]
References
[1] Molecular Cancer Therapeutics 2011; 10: 1028
Attention
Sold for research purposes only; not for human, medical, veterinary, food or household use.
