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Name:Afatinib(BIBW2992)
Chemical structure | Code NO. |
MT0011 |
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Name |
Afatinib(BIBW2992) |
Synonym |
Afatinib,BIBW2992 | |
CAS NO. |
439081-18-2 | |
Chemical Formula |
C25H27ClFN5O2 | |
MW |
483.96 | |
Purity |
>98% | |
Solubility(R.T.: 25℃) |
DMSO ≥97mg/mL, Water <1mg/mL , Ethanol ≥97mg/mL | |
Stability |
- 20℃, 2 years |
Availability and price
Afatinib(BIBW2992) is in stock. Bulk available at low price, welcom to inquire quotation.
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Description
Afatinib is an irreversible ErbB-family blocker, has shown preclinical activity when tested in EGFR mutant models with mutations that confer resistance to EGFR tyrosine-kinase inhibitors.[1]
References
[1] The Lancet Oncology, 13(5): 528-538
[2] Lancet 2010;375: 1437–1446
Attention
Sold for research purposes only; not for human, medical, veterinary, food or household use.